be down and out meaning in English

被击倒而停止比赛, 穷困潦倒

Never give up on wishes , when you are down and out
永远不要放弃祈愿，当您失望难过的时候。
He has been down and out ever since the factory closed
自从工厂关闭之后，他就一直穷困潦倒了。
Though the writer have been down and out , he still keep on writing
那个作家虽然已经穷困潦倒了，但他还是继续写作。
Be down and out
被击倒而停止比赛
Many of the lakers were down and out , really in no mood for exit meetings with phil jackson and mitch kupchak after another early playoff elimination last may
在经过上赛季五月又一次的季后赛第一轮淘汰后，大多数球员都很失落，他们都没有心情去理会禅师和米奇?库普切克在总结会上所说的话。